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Background: Irrational use of prescribing medicines is on the rise due to many factors. The Resident doctors are exposed to variety of prescribing patterns in their daily clinical practice. Aim and Objectives: The study was planned to assess the knowledge, attitude, and practice of rational use of medicine among Resident doctors in a tertiary care teaching hospital. Materials and Methods: A cross-sectional questionnaire-based study was conducted among Resident doctors at a tertiary care teaching hospital. Permission was obtained from the Institutional Ethics Committee. The participants were explained about the study and consent was taken. Identity of the residents was kept confidential. Questionnaire was designed to obtain information about the knowledge, attitude, and practice of Rational Use of Medicines (RUM). The data were recorded and analyzed, and the results are explained in frequency and percentage. Results: About 98% were aware about the term RUM and 96% practiced it, only 9% had National List of Essential Medicines of India available at their work place and 68% were able to correctly name the parts of the prescription slip. 88% respondents were aware about Essential Medicines (EM) and 86% prescribed them. Conclusion: In our study, majority of the Resident doctors were aware about EM and their importance. However, the level of understanding related to P-drug concept and existence of Essential Medicine List was limited. Thus, it is necessary to implement institutional guidelines to achieve more appropriate prescribing patterns, to promote prescription based on the list of EM.
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Background: P-drug is a personal or preferred or priority choice drug of a clinician. The aim of the study is to evaluate knowledge, awareness, practice of p-drug which helps the clinician to prescribe drugs rationally.Methods: The study was a prospective cross-sectional pre-validated questionnaire-based study conducted in Government General Hospital, Rangaraya Medical College, Kakinada. During the study period a total of 300 members were enrolled and instructed to fill the questionnaire forms. These filled forms were collected and data were analyzed.Results: Out of 300 members, 240 filled the questionnaire, and these forms were evaluated. Among them 16.6% were aware of p-drug, 27.5% were aware of P treatment, 32.5% were not including FDC抯 in their p drug list, 28.33% were aware of advantages of prescribing P drug and 82% felt that teaching programs were needed for preparing p drug list.Conclusions: For promoting and achieving rational use of medicine, P drug concept is one of the milestones. As few were aware of p-drug concept, institutional teaching review board should conduct teaching programs regarding p drug concept.
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OBJECTIVE: To investigate the use of antibacterials for patients with acute upper respiratory tract infections(AURIs) in community health care institutions in Dongcheng district, so as to provide references for rational use of antibacterials in primary health care institutions. METHODS: All the outpatient prescriptions of AURIs patients from 65 primary health care institutions in Dongcheng district in 2016 were selected. The antibacterial and multiple antibacterial prescription rate were analyzed from the perspective of drug categories, patients′ and doctors′ characteristics. RESULTS: This study included 164 575 AURIs prescriptions of community health care institutions in Dongcheng district in 2016. The antibacterial prescription rate(APR)was 12.1% and the multiple antibacterial prescription rate(MAPR) was 0.6%. The top antibacterials in the list of varieties were second generation cephalosporin(60.2%) and macrolide(16.2%), the penicillin preferred by the guidelines were not used. The APR for the male and patients with acute laryngitis or acute tonsillitis was higher. Compared with patients 18-50 years old,the use and combination of antibacterials for patients >50 years old werehigher(P<0.05).There were significant differences in the use and combination of antibacterials among doctors of different genders, education and titles(P<0.05). CONCLUSION: The issue of antibacterial abuse in the AURIs treatment in primary health care institutions should be given sufficient attention. Regular standardized antibacterial treatments training and continuing education for all doctors in primary health care institution are necessary.
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Background: The concept of generic prescription is widely accepted in various parts of the world. Nevertheless, it has failed to gain popularity in India due to factors such as non-availability and distrust on the product quality. Aim: To study cost-effective and cost-benefit analysis of antibiotic prescription in patients who had enteric fever and were given intravenous ceftriaxone. Methods: This was a prospective observational study conducted in a tertiary care cenre at World College of Medical Science and Research, Jhajjar, Haryana. 65 patients who have been diagnosed with enteric fever and were prescribed ceftriaxone were studied and their prescriptions were analyzed. 5 brands of most commonly prescribed ceftriaxone injections were chosen to analyse cost effective and cost-benefit analysis. Results: Out of 65 patients, 40 were females and 25 were males, diagnosed with enteric fever. Maximum number of patients were seen between age group of 36-50 years (38) and minimum patients belonged to age group of more than 65 years. Analysis of prescriptions revealed that majority of the patients were prescribed Branded drugs 53 (82%) than were prescribed generic drugs 12 (18%). The analysis of the cost of single dose of inj. ceftriaxone revealed that branded drugs were 8.52 % to 180.81% more in comparison with generic IV ceftriaxone. Conclusion: The cost of most commonly prescribed branded drugs was significantly higher than generic drug and prescribing branded drugs was associated with failure to take complete treatment as prescribed by treating physician.
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The term therapeutic jungle coined by pharmacologist Louis Goodman refers to combination of overwhelming number of drugs the confusion of nomenclature and associated uncertainty of the status of many of these drugs. Rational drug policy, rational people behavior, rational prescription is the need of hour. Polices determine the availability of medicine in term of production pattern distribution marketing pricing and drug usage. India’s pharmaceutical industry is mighty, with over Rs 2 lakh crore worth of medicines and vaccines, produced and supplied by over 7,000 manufacturing units. It caters to not only the domestic market, but it also exports to over 200 countries.
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As an essential part of modern medical service,pharmaceutical care gains more and more attention in the field of medication. The goal of pharmaceutical care is to effectively control rational administration of drugs, improve the therapeutic efficacy and avoid adverse drug reactions.Pharmacology,as the key basis of pharmacy,directly determines the level of pharmaceutical care.Therefore,development of pharmacology,especially for the clinical pharmacology,plays an important role in enforcing capability of clinical pharmacists.In this article,we summarized the functions of medical care in medical practice based on the Chinese medication.Authors described the relationship of pharmacology and medical care in the medication for cancer, infectious diseases, and chronic diseases. Authors proposed that the rational drug administration under the guidance of pharmacology is the core point to evaluate the quality of clinic pharmaceutical care,and the final goal of which is to increase the benefit of medication and guide the training of pharmacists in China.
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Objective The national essential medicine select system is the core of Chinese medicine policy.How to select drugs fundamental for eyes scientifically is an important ring in establishing the Chinese essential drug system.The present study attempted to compare the National Essential Medicines List and National Essential Insurance List of China with that of the WHO in order to provide reasonable evidence for the adjustment of a new National Essential Medicines List of China. MethodsThe WHO Essential Medicine List (15th edition,Version in 2007),National Essential Medicine List (Version in 2009,China),2009 National Essential Medicine List Chemical Medicine Name (Version in 2009) and National Essential Insurance List of China (Version in 2004) were reviewed.The similarity and difference in the category and number of drugs in the National Essential Medicines List and National Essential Insurance List between China and WHO were compared and analyzed.A descriptive method was adopted to analyze the sorts and numbers of eye drugs in the lists mentioned above.The analysis of drug price was based on the summary sheet from Zhejiang Province. ResultsLittle difference was found in the numbers of eye drugs between the National Essential Medicines List of China and WHO Essential Medicines List.Differences in the sorts of eye drugs were observed in the lists,especially between the National Essential Medicines List of China and WHO Essential Medicines List.Except for levofloxacin,all of the drugs in the National Essential Medicine List of China were included in the National Essential Insurance List of China.ConclusionThe selecting principle and renewing procedure of the National Essential Medicines List and National Essential Insurance List of China should be further improved in China based on the list from WHO.More attention should be paid to the standard,dosage form,affordability,maneuverability etc.during the selecting procedure of eye essential drugs.
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Irrational use of medicine has some reasons subjectively and objectively.Under a system of new framework,the key link of achieving rational medical use is that how to strengthen the effeetive regulation.Construeting a scientific surveillance system.innovating monitoring system,intelligent using of modern management techniques,controlling the entire process of the implementation of medicine,to promotion the rational use of medicineprovides a strong institutional guarantee and technical support.
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OBJECTIVE:To promote the rational use of Chinese patent medicines in treating acne.METHODS:The composition,efficacy,property and indications of the common 12 kinds of patent Chinese medicines used for treating acne were analyzed respectively.RESULTS: The basis for the treatment of acne is clearing away the heat-evil and expelling superficial evils.Based on the potency in clearing away the heat-evil and expelling superficial evils,the 12 patent Chinese medicines can be divided into 3 groups.CONCLUSION: In treating acne,the Chinese patent medicines used for clear away the heat-evil and expel superficial evils should be considered preferably based on the degree of pyretic toxicity followed by the choice of the matched drugs if accompanied with other pathogenic factor.